Atropine-neostigmine mixture

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Timing of atropine and neostigmine in the reversal of muscle relaxants.

The antimuscarinic effects of atropine were studied in 46 patients to whom neostigmine had been given after operation to reverse the action of a muscle relaxant. Neostigmine was given to alternate patients three minutes after, or together with, atropine, and the effects of the two procedures were compared by measuring the secretions which collected in the buccal and oropharyngeal cavities and o...

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Effects of Atropine Sulphate and Neostigmine Treatments on Rabbit’s Harderian Gland

The harderian gland is a compound tubuloacinar gland located around the posterior aspect of the eye ball in the majority of land vertebrates. Despite this gland has been comprehensively studied in several mammalian species, little studies tackled the lagomorph’s harderian gland. The present study was undertaken to describe the structure of the rabbit (Oryctolagus cuniculus) harderian gland and ...

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Heart rate changes in halothane anaesthesia: effect of varying doses of atropine and neostigmine.

Heart rate changes during halothane-tubocurarine anaesthesia (Group I, 60 patients), and pethidine-tubocurarine (Group II, 20 patients) have been studied. Significant changes were noted immediately after thiopentone induction, after intubation and after atropine 1.2 mg, 1.8 mg, or 3.0 mg. It was found that atropine 1.8 mg was as effective as atropine 3.0 mg in increasing heart rate, Atropine ca...

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Sugammadex reversal of rocuronium-induced neuromuscular blockade: a comparison with neostigmine-glycopyrrolate and edrophonium-atropine.

BACKGROUND Sugammadex is a modified [gamma] cyclodextrin compound, which encapsulates rocuronium to provide for a rapid reversal of residual neuromuscular blockade. We tested the hypothesis that sugammadex would provide for a more rapid reversal of a moderately profound residual rocuronium-induced blockade than the commonly used cholinesterase inhibitors, edrophonium and neostigmine. METHODS ...

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Effects of neostigmine and atropine on motor activity of ileum, colon, and rectum of anaesthetized subjects.

In unanaesthetized patients atropine and neostigmine in doses normally used by anaesthetists to reverse muscle relaxants produced a pronounced increase in bowel activity. This response occurred whether atropine was given before or simultaneously with neostigmine.The response still occurred in 38% of patients anaesthetized without halothane, and possibly this increase in motility might endanger ...

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ژورنال

عنوان ژورنال: Canadian Journal of Anaesthesia

سال: 1990

ISSN: 0832-610X,1496-8975

DOI: 10.1007/bf03005489